What's in a Gene Pseudoexfoliation Syndrome and Pigment Dispersion Syndrome in the Same Patient
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چکیده
منابع مشابه
What's in a Gene? Pseudoexfoliation Syndrome and Pigment Dispersion Syndrome in the Same Patient
Pseudoexfoliation syndrome (PXS) and pigment dispersion syndrome (PDS) are two of the commonest disorders to produce secondary open-angle glaucoma through trabecular meshwork blockage. Each is a defined clinical entity, and while genetics likely play a significant role in the pathogenesis of both, the specific genes involved appear to be distinct. There is surprisingly little published in the l...
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OBJECTIVE: Pseudoexfoliation syndrome (PEX) leads to some problems in the eye surgery specially cataract surgery. As the prevalence of eye problems is high in diabetic patients, we meant to assess the prevalence of PEX in diabetic patients. MATERIALS AND METHODS: In this cross-sectional study, 400 type 2 diabetic patients aged 50 or above who referred to Yazd Diabetes Research Center were sele...
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OBJECTIVE To assess aqueous humor dynamics in pigment dispersion syndrome (PDS). METHODS Four groups of age-matched participants included 2 experimental groups with PDS (PDS with ocular hypertension [PDS-OHT], 17 eyes; PDS without ocular hypertension [PDS-ONT], 18 eyes) and 2 control groups without PDS (OHT, 18 eyes; ONT, 18 eyes). Assessments included intraocular pressure measured by pneumat...
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PURPOSE To identify and characterize genes differentially expressed in anterior segment tissues of eyes with pseudoexfoliation (PEX) syndrome and glaucoma. METHODS Anterior segment tissues (iris, ciliary processes, lens epithelium) were obtained from eight surgically enucleated eyes with PEX-associated open-angle or closed-angle glaucomas and eight age-matched glaucomatous control eyes withou...
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This study involved a group of 407 patients (799 eyes) with pigment dispersion syndrome gathered from a glaucoma population of 9200 patients. The sex distribution was equal. The majority (65%) of patients were myopic. The incidence of retinal detachment was 6.4%. No patients were black, but 5 were mulatto. Approximately one-quarter of the patients wih pigment dispersion syndrome (31% of the men...
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ژورنال
عنوان ژورنال: Case Reports in Ophthalmology
سال: 2016
ISSN: 1663-2699
DOI: 10.1159/000443697